Ectopic ACTH Syndrome Due to Thymic Atypical Carcinoid Treated with Combination Chemotherapy of Cisplatin and Etoposide
نویسندگان
چکیده
منابع مشابه
Ectopic ACTH syndrome due to thymic atypical carcinoid treated with combination chemotherapy of cisplatin and etoposide.
A 21-year-old woman with Cushing's syndrome presented with a mediastinal tumor. Ectopic ACTH syndrome was diagnosed and the tumor was resected. The histopathological diagnosis was thymic atypical carcinoid. Despite all tumor lesions having been resected, the tumor relapsed and multiple metastatic lesions grew aggressively. Combination chemotherapy with cisplatin and etoposide (VP16) was adminis...
متن کاملFulminant Cushing's syndrome due to an ACTH-producing thymic carcinoid.
Case Description A 32-year-old man was hospitalized because of severe fatigue and blurred vision. Evaluation revealed glaucoma, hypertension, new-onset diabetes mellitus and severe hypokalemia with metabolic alkalosis. A month later he was admitted to the urology department because of a perianal and scrotal abscess, which was surgically drained. Following surgery, he developed shortness of brea...
متن کاملCyclical Cushing's syndrome due to an atypical thymic carcinoid.
A 43-year-old man presented with fluctuating symptoms of weight gain, shortness of breath, pretibial oedema, associated with anxiety and memory disturbances. Laboratory investigation revealed an adrenocorticotropin (ACTH)-dependent cyclical Cushing's syndrome characterised by remarkable variations in urinary cortisol excretions ranging from 27 to 28,050 nmol/ 24 h. Magnetic resonance imaging (M...
متن کاملCisplatin and Etoposide Combination Chemotherapy
Background: Thymomas are rare neoplasms of the mediastinum. The role of chemotherapy in advanced thymomas is not fully established. Patients and Methods: In the European Organization for Research and Treatment of Cancer (EORTC) Lung Cancer Cooperative Group, 16 patients with recurrent or metastatic malignant thymoma were entered over 6 years onto a study of combination chemotherapy that consist...
متن کاملCushing's Syndrome due to Ectopic ACTH from Bronchial Carcinoid: A Case Report and Review
Despite advances in analytic and imaging techniques, the syndrome of ectopic adrenocorticotrophic hormone (ACTH) secretion from a tumour resulting in Cushing's syndrome continues to pose difficult diagnostic and therapeutic challenges. Dynamic testing may be equivocal and radiology indeterminate. We report a patient presenting with Cushing's syndrome associated with ectopic ACTH secretion from ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Internal Medicine
سال: 2003
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.42.1197